What is CBG? READ THIS before you buy CBG online!

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What is CBG and should you buy CBG online?

Has anyone told you recently to buy CBG online? We know that CBD is all the craze, but as more research unfolds, additional cannabinoids like CBG and CBN are slowly becoming available. Here at Nexus Botanicals, our mission is to create the Nexus of Science and Nature™, providing customers with the highest quality, scientifically formulated natural products.

Further, we want to bring helpful information forward to educate consumers. There is a lot of misinformation available online surrounding various cannabinoids and how they work.

Given the excitement around the burgeoning cannabis industry, consumers are becoming increasingly educated about what the cannabis plant is and what the derivatives of the plant are. There are at least 120 chemical compounds found in the plant, and science has just scratched the surface toward the goal of a more thorough understanding of cannabis, cannabinoids, and the interplay of the various other plant compounds found in the cannabis plant.

By now, most people are familiar with the most popular derivatives of the cannabis plant, including tetrahydrocannabinol (THC) and cannabidiol (CBD). Many people are, however, not as familiar with some of the differences between the difference derivatives, including the fact that CBD is non-psychoactive.

A large number of people are just learning that there are many more similar compounds found in the cannabis plan. One of the lesser-known but up-and-coming cannabinoids is called cannabigerol (CBG). CBG is typically not present in large quantities in most cannabis strains, but it is still an important compound to learn more about.

 

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The most well-known cannabinoids include:

  • Tetrahydrocannabinol (THC).
  • Cannabidiol (CBD).
  • Cannabigerol (CBG).
  • Cannabinol (CBN).
  • Cannabichromene (CBC).

 

Want to be one of the first to buy CBG online?

Join our wait-list to buy CBG for sale online. Nexus Botanicals will be launching a range of CBG products, as soon as formulation is complete!

 

CBG is not the same thing as CBD

CBG can be considered the parent of all cannabinoids, as research indicates that every cannabinoid starts as CBG and becomes other cannabinoids such as THC or CBD as the plant matures.

Research to date has shown that as the cannabis plant matures, CBG-A, the acidic form of CBG, is converted by the plant to tetrahydrocannabinolic acid (THC-A), cannabidiolic acid (CBD-A), and cannabichromenic acid (CBC-A). The ratios between the three compounds can vary greatly.

CBG is formed through decarboxylation from the amounts of CBG-A that have not been converted into any of the other compounds (THC-A, CBD-A or CBC-A). As a result of the decarboxylation process, most cannabis strains typically contain a minimal concentration of CBG – as little as less than 1 percent. Researchers have been experimenting with genetic manipulation and crossbreeding in order to try to obtain higher yields of CBG. 

There is some research that indicates CBG may be more effective for users than CBD. Similar to CBD, CBG does not have the psychoactive effect on users that THC does. This makes it attractive for further research.

 

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How is CBG made?

Due to the fact that CBG is found in low levels in most cannabis strains, CBG is considered to be a minor cannabinoid. By definition, cannabis plants produce CBG-A, which is converted to the three main cannabinoid lines: THC-A, CBD-A, and CBC-A.

There are unique enzymes in the plant that break CBG-A cause it to transition to one of the three main cannabinoid lines. These compounds are exposed to high temperatures or ultraviolet lights, causing them to transition to one of the most well-known compounds including THC and CBD.

In most strains, CBG-A is transformed into THC-A or CBD-A. This means that because CBG-A is converted into THC or CBD, it is not converted to CBG. As further research is done and the market demand increases, CBG production will follow.

As market demand increases and larger yields of CBG are required, cannabis plant breeders are experimenting with genetic manipulation and the cross-breeding of plants.

 

What does the research say about CBG?

CBD is one of the most popular compounds available on the market. However, the mechanisms of action of CBD as a standalone compound requires further research. This is why Nexus Botanicals products are only made with premium broad-spectrum hemp oil extract containing CBD, other trace cannabinoids, and what together is believed to create the “entourage” effect. Unlike CBD, which has a lower absorption rate by cannabinoid receptors and acts mostly through indirect interactions with the endocannabinoid system, researchers believe that CBG’s therapeutic effects are delivered directly to the cannabinoid receptors in the brain. This is part of the reason why so many people want to buy CBG products.

THC is known to produce its psychoactive effects though interactions with the cannabinoid receptors. Conversely, CBG has shown to work as a buffer or counterbalance to THC’s psychoactive effects. It has also been shown to alleviate feelings of paranoia that can be a result of the consumption of high levels of THC.

The market’s knowledge base for CBG is still relatively light regarding its therapeutic benefits for consumers. This is unique to CBG compared to the expansive amount of information available on THC and CBD within the cannabis industry.

There are some early studies which link CBG to quite a few potential therapeutic uses including:

  • A new treatment for glaucoma.
  • Treating inflammation and inflammatory bowel diseases such as Crohn’s disease.
  • Combating Huntington’s disease, Parkinson’s disease, multiple sclerosis and other movement diseases.
  • Inhibiting tumor growth.
  • Killing drug-resistant bacteria.
  • Anxiety disorders.

 

There has been research suggesting CBG may be successful as a potential antibiotic, as well as for pain and inflammation reduction. There is even the potential that CBG can be used in slowing the growth of cancer cells. To date, CBG’s effects have not been studied in human adults

The research that has been done to date is exciting in its potential and leaves the door open for future successes for CBG derivatives.

CBG has been listed as an ingredient in some oils and tinctures across the cannabis industry, but it is important to note that due to lacking or unclear regulations for CBD and CBG products across the United States, it’s difficult to fully understand the concentration or contents that you’re really getting in any product. It is also very important to note that there is minimal research in how CBG, as well as other derivatives of the cannabis plant, interact with other medications that one may take.

Many may not be aware, but every person has a built-in endocannabinoid system (ECS) that works to keep the body in a state of homeostasis. The ECS works across the entirety of the body, serving multiple functions depending on the body’s need. In simple terms, the ECS acts as the air traffic controller for the human body.

CBG has been found to have an effect on physiological systems and can be used to address specific problems. Endocannabinoid receptors are thought to be significant in the eye. CBG is thought to be potentially effective in treating glaucoma. CBG has been found to be effective in decreasing the inflammation typical of inflammatory bowel disease such as Crohn’s disease. CBG has been shown to protect neurons in preliminary and exciting research. CBG is showing potential as a treatment option for cancer patients. CBG has been shown to potentially block receptors that cause cancer cell growth.

Researchers have become intrigued about the initial returns on CBG research, and are excited for future research with CBG as a stand-alone compound or in combination with other cannabinoids and therapies for the treatment of potentially countless diseases and disorders. Due to its non-psychoactive properties, CBG has a promising and wide array of potential applications.

 

Want to be one of the first to buy CBG online?

Join our wait-list to buy CBG for sale online. Nexus Botanicals will be launching a range of CBG products, as soon as formulation is complete!

 

Is CBG the next big thing? Where can I buy CBG?

CBG has been one of the newest and fastest growing areas of research by many groups throughout the cannabis industry. It is important to note that CBG does not have the same psychoactive effect as THC. Those researching CBG believe that it may help mitigate anxiety that can be felt by users of THC products.

If you are one to follow wellness trends in the market, then you are most likely familiar with the significant number of CBD products that have become readily available on the market over the last few years. CBD oils, topicals, and capsules are still quite popular across the country when it comes to healing and relaxation. Given the popularity of CBD products, there is significant interest in testing the market for other cannabis plant derivatives, including CBG.

Why has there recently been a push for CBG research and market development? Some of this can be traced to the greater acceptance of cannabis in the United States. In the 2020 election, five new states passed new medical and/or adult use cannabis programs. A recent survey shows that two out of three Americans approve of legalized cannabis.

At a more micro level, it may be due to the fact that there is an increased understanding of cannabis and cannabinoids. As a result, this push for cannabis research and evaluation has introduced scientists to many new cannabinoid compounds in addition to the more well-known THC and CBD. Furthermore, advances in extraction and isolation technology have allowed scientists to be able to isolate many cannabinoids, including CBG, which was just not possible or common even a few years ago.

A key aspect of CBG, amongst other cannabinoid compounds, is that they have been found to be very active from a pharmacological standpoint. This means that they interact with a number of different receptor systems in the human body, including the endocannabinoid system. These systems are involved in nearly every aspect of human physiology from metabolism to pain perception and beyond.

Take the endocannabinoid system for example, which consists of CB1 (found in the central nervous system) and CB2 (found in the immune system) receptors and its associated enzymes. The ECS interacts to a significant degree with cannabinoids. This is very similar to how pharmaceutical drugs work with the human body, by interacting with receptor systems to initiate desired results and a specific health result.

 

CBG is difficult to produce.

CBG is known to have no psychoactive effects, and research is showing the potential for therapeutic uses.  This raises a fundamental question: why is CBG not as popular as CBD?

As with most things, economics play a major role in why CBG is not as popular or widely distributed as CBD. The biggest obstacle to CBG becoming a common therapeutic treatment is the cost of its production. CBG is currently one of, if not the most, expensive cannabinoids to produce in the market.

As discussed previously, CBG is required to produce THC and CBD which are in higher demand. It can be an extensive process to acquire enough biomass to produce a significant enough amount of CBG.

CBG can present a challenge to cultivators, which is unique amongst cannabis derivatives. The more time that a cannabis plant has to mature, the more likelihood there is that the CBG-A in that strain will be converted into other cannabinoid derivatives. This challenge causes cultivators to have to make a choice: grow cannabis plants purely for the purpose of producing CBG or allow the plants to fully mature. To produce CBG, a cultivator would have to harvest the plant early before the transition to another cannabinoid completes.

In addition to requiring greater amounts of plants compared to THC or CBD, CBG extraction also requires the use of specialized production equipment. Due to the low levels of CBG that are present in most cannabis strains, the chromatography apparatus that is used in the extraction process for CBG needs to be precise so as to not necessitate the use of even more raw plant material than is absolutely needed. The cost to acquire and maintain the high-performance chromatography machine can be a significant and immediate production/fixed asset cost for processors and manufacturers who may not already own and operate this equipment in their standard processing operations.

Products containing CBD have absolutely exploded in popularity and distribution over the past few years, as CBD has earned a reputation for its benefits. This has made CBD into a trendy ingredient for myriad products across multiple consumer sectors. It is reasonable to expect that CBG will have a similar journey through the market as it matures.

CBD is known to be the major non-psychoactive component in cannabis, as CBD is abundant in common cannabis strains. This makes CBD’s isolation process and use easily translatable to operations across multiple consumer markets. This is an incredible precedent for CBG.

CBG may be derived from the same plant as CBD, but there are fundamental differences between the two which we are just beginning to scratch the surface on. This is an exciting time to see what is next for CBG and how the market will accept it.    

 

Join our wait-list to buy CBG for sale online. Nexus Botanicals will be launching a range of CBG products, as soon as formulation is complete!

 

Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021502/

Disclaimer: Nexus Botanicals does not make any medical or use claims about our products. Our products are sold as botanical products. Always consult with a licensed healthcare practitioner.

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